In collaboration with the University of Ghana, we are pleased to announce this Wellcome Genome Campus Overseas Course in Malaria Experimental Genetics.
This free laboratory-based course will provide participants with hands-on training in cutting-edge Plasmodium experimental genetics techniques, from designing gene targeting vectors and creating transgenic parasites to genotyping and phenotyping the resulting strains.
The goal is to facilitate the participants’ own research careers by exposing them to state-of-the-art experimental approaches, while discussing the advantages and limitations of each approach.
The week-long course will cover experimental approaches to generating genetic mutations in the human malaria parasite Plasmodium falciparum. The course is hands-on and attendees will generate gene targeting constructs, carry out different transfection approaches, undertake practical exercises in genotyping of modified parasites, and both observe and learn advanced molecular phenotyping approaches.
There will be a particular focus on new scalable approaches, including CRISPR-Cas9 genome editing. Experimental genetic approaches in other malaria parasites including the rodent malaria model Plasmodium berghei and the human pathogen Plasmodium knowlesi will also be discussed. The laboratory-based programme will be complemented by specific lectures
in cutting-edge areas presented by distinguished regional guest
The course is open to scientists and clinicians based in Africa who are looking to establish and use Plasmodium transfection technology at their institutes. Places are limited and priority will be given to applicants who provide a strong scientific case for learning Plasmodium genome modification.
The course will be taught in English.