This course provides an overview of the molecular basis of neurodegeneration and the development of therapeutic intervention to combat neurodegenerative disorders. The programme will focus on several disorders including Alzheimer’s disease, Parkinson’s disease, Fragile X, Spinocerebellar ataxia and amyotrophic lateral sclerosis. There are many parallels between different neurodegenerative disorders and the course will examine the common themes across neurodegenerative processes. Participants will gain an insight into the current understanding of both rare and common neurological disorders, the strengths and weaknesses of experimental approaches and evidence, recent developments in biomarkers and how this knowledge can be applied to develop therapies.

The programme is aimed at individuals working in neurodegenerative research, neurogenetics or translational neuroscience, including clinician scientists, veterinary scientists, PhD students and post-doctoral researchers. We encourage applications from researchers based in the pharmaceutical and biotechnology industries. Applications from those who have completed a PhD in another area and have moved into neuroscience for their postdoctoral studies will also be considered.

The course will benefit researchers who seek a comprehensive view of neurodegenerative disorders together with state of the art research techniques, and who wish to gain a new perspective on their own studies. The intensive programme provides the opportunity to interact with leading international neuroscientists. To optimize discussions and interactions, numbers are limited to 30 students.

Learning outcomes
After attending this course, participants will be able to:

•    Describe in detail the process of neurodegeneration
•    Compare and contrast different neurological disorders
•    Critique a range of experimental techniques being used in neurogenetics
•    Interpret and communicate the findings of a Genome-Wide Association Study
•    Discuss the use of multiple biomarkers to diagnose neurodegenerative diseases
•    Describe recent advances in therapeutic and translational areas to prevent and treat neurodegenerative diseases
•    Apply concepts learned on the course to your own research project

Feedback from previous participants

“The whole course was an amazing experience and a great opportunity to get up to speed in such complex topics.”

“The course really broadened my horizons as to the different powerful tools used for studying the mechanisms of disease.”

“This is the best course I have been on. The interactive element to the course with fantastic speakers and a small group of participants is truly unique. The speakers and topics chosen perfectly complemented each other. By the end of the course key mechanisms and therapeutic strategies across the breadth of the neurodegenerative diseases were highlighted with important common themes emerging across diseases. I came away with lots of ideas to take to the lab.”

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