Next generation sequencing has become an essential tool in genetic and genomic analysis. It is increasingly important for experimental scientists to gain the bioinformatics skills required to assess and analyse the large volumes of sequencing data produced by next generation sequencers. This next generation sequencing bioinformatics course aims to equip participants with the essential informatics skills and knowledge required to begin analysing next generation sequencing data and carry out some of the most common types of analysis.

The course programme will cover the algorithmic theory and principles of bioinformatics, with a strong focus on practical computational sessions using sequence analysis techniques and tools applicable to any species or genome size. Accompanying the lecture and practical sessions will be a series of seminars by invited speakers, who will highlight their ground-breaking work in applications of next generation sequencing.

This course is open to applicants from Latin America and the Caribbean. The course is free to attend for non-commercial applicants. Limited bursaries to cover travel, accommodation and sustenance costs are also available. The course will be taught in English with language support from regional instructors.

Learning Outcomes
On completion of the course, participants can expect to have acquired:

  • A working knowledge of the unix command-line and writing basic shell scripts for automating bioinformatics tasks
  • Knowledge of how to do QC assessment of high throughput sequencing data
  • Understanding of the algorithmic concepts behind short read alignment and variant calling, and practical experience using the software
  • Experience analysing RNA-Seq and CHiP-seq data for measuring abundance
  • Knowledge of the organisation and sequencing data types available in public sequencing repositories
Please note: The practical sessions will be taught exclusively through Unix/Linux. Therefore, participants are required to have some previous exposure of using the Linux operating system. This will be essential for participants to fully benefit from the course.

There are numerous online introductory tutorials to the UNIX/Linux operating system and commad line, including:
http://rik.smith-unna.com/command_line_bootcamp
http://www.ee.surrey.ac.uk/Teaching/Unix
http://swcarpentry.github.io/shell-novice/

The course aims to provide a hands-on introduction to bioinformatics for next generation sequencing, and should not be considered a complete education in the theoretical and mathematical foundations of the topics.

Related courses
Applicants working on bacterial and eukaryotic pathogens may wish to consider our Working with Pathogen Genomes course, which is scheduled to run in Uruguay late 2018.

Email us for notification when this course opens for applications.
Details of the current course content can be found by clicking here.

Application Deadline:
3 November 2017

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(or call us: +44 (0)1223 496910)


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