This course type is laboratory

Chromatin Structure and Function

26 October - 04 November 2015Wellcome Genome Campus, Hinxton, UK
Deadlines (at 23:59 UTC):
  • Application Deadline Closed

  • Summary

    This popular course will provide training in the experimental and
    computational approaches that can be used to mechanistically dissect
    important aspects of chromatin biology at the gene or genome-wide levels.

    Our understanding of complex genomes has benefitted tremendously from
    whole genome sequencing projects. However, we are only beginning to
    systematically understand how the interplay of DNA, proteins and its
    biochemical modifications (i.e., chromatin) can influence global
    processes which control gene expression, mRNA splicing, and DNA
    replication or repair in normal development and in disease.

    Feedback from the (inaugural) 2014 course:
    “This has been by far the most useful course I have attended. I
    really enjoyed the course. The techniques will be very useful to me for
    my research.”
    “The course was excellent. The instructors and assistants were very
    knowledgable, and very accessible.”
    “The course was amazing with great instructors.”
    “It was a very good course that will definitely impact the careers of the

  • Programme

    Participants will receive intensive laboratory and computational training in state-of-the-art approaches focussed across five broad themes:

    • DNA/transcription factor interactions
    • DNA methylation
    • Histone dynamics and modifications
    • Chromatin accessibility, looping and nuclear organisation
    • Computational analysis/integration of chromatin datasets

    These sessions will be supplemented with informal tutorials and lectures from the instructors and distinguished invited speakers. Participants will analyse the various genome-wide data generated in parallel to or during the laboratory sessions. They will also have an opportunity to discuss their own research interests and present aspects of their work that are relevant to the course.

  • Instructors / Speakers

    Course instructors
    David Vetrie University of Glasgow, UK
    Nick Gilbert University of Edinburgh, UK
    Lee Butcher Imperial College London, UK
    Robert Andrews Cardiff University, UK

    Guest speakers
    Frank Pugh Penn State University, USA
    Jim Hughes University of Oxford, UK
    Leonard Schalkwyk University of Essex, UK
    Cameron Osborne King’s College London School of
    Medicine, UK

  • How to Apply

    Applicants should be senior PhD students or post-doctoral scientists
    engaged in relevant research.

    course is subsidised by the Wellcome Genome Campus Advanced Courses
    and Scientific Conferences Programme. This is a residential
    course and
    there is a fee of £1045 towards board and lodging for non-commercial
    applicants. Please contact us for the commercial fee.

    Applications for this course can be completed online. If you have any
    problems with the online application process, please contact us.

    Please note: Applications
    must be supported by a
    recommendation from a scientific or clinical sponsor (e.g. supervisor or
    head of department). A request for a supporting
    statement will be sent
    to your nominated sponsor automatically during
    the application process.
    Applicants must ensure that their sponsor
    provides this supporting
    statement by the application deadline. Applications without a supporting
    statement cannot be considered.


  • Bursaries

    Advanced Courses are subsidised for non-commercial
    applicants from anywhere in the world. Additional, limited bursaries are
    available (up to 50% of the course fee) and are awarded on merit. If you
    would like to apply for a
    bursary, please complete the bursary section
    of the online application

    Please note that both the applicant
    and sponsor are required to provide
    a justification for the
    bursary as part of the application.

    Bursary terms and conditions

    UK Courses (held at the Wellcome Genome Campus, Hinxton,
    limited number of bursaries are available for each course. These are
    awarded by the selection committee according to merit. The bursary
    covers a maximum of 50% of the course fee, though in exceptional
    circumstances an application for the total course fee may be considered.
    Where there are many bursary applications, the selection committee may
    issue smaller amounts. We cannot assist with travel costs to attend UK

    Overseas Courses (held outside of the UK)
    limited number of bursaries are available for each course. These are
    awarded on merit to cover travel, accommodation and sustenance. The
    maximum award for travel (economy class) will be £750.

    Bursaries can be applied for as part of the course application form.
    will be notified of a bursary award along with their place on
    course, usually within one month of the application deadline. The
    decision of the selection committee is