Devising a Consensus Framework for Validation of Novel Human Coding Loci

11 - 13 May 2015Wellcome Genome Campus, UK

  • Summary

    The chromosome-centric Human Proteome Project (c-HPP) is a large multidisciplinary international effort to catalogue human gene products, focusing on so-called ‘missing proteins’, those which have little evidence at the protein level. Aprox 18 % of the human proteome lacks evidence at the protein level. This retreat brought together experts from the fields of genomics, transcriptomics, proteomics, and representatives from the major human genome and protein databases, to establish guidelines to validate human protein products. In addition set of standard guidelines were developed that the biocuration and scientific community can use to determine the evidence required to a novel coding loci being added or removed from the reference human gene sets (UniProt, GENCODE and RefSeq).

  • Scientific committee

    Scientific programme committee

    Jen Harrow

    Jen Harrow
    Wellcome Sanger Institute, UK

    Elspeth Bruford

    Elspeth Bruford
    European Bioinformatics Institute, UK

    Amos Bairoch

    Amos Bairoch
    NeXtProt, Switzerland

    Lydie Lane

    Lydie Lane
    NeXtProt, Switzerland