This course type is laboratory

Genomics and Clinical Microbiology

21 - 26 January 2018Wellcome Genome Campus, Hinxton, UK
Deadlines (at 23:59 UTC):
  • Application Deadline Closed

  • Summary

    The future of microbiological diagnostics and infection epidemiology is
    increasingly centred on rapid molecular testing and the application of
    sequencing technology. Practitioners in these disciplines will have to
    process and interpret such data, which is very different from the
    familiar agar-centric clinical microbiology laboratories.

    The Genomics and Clinical Microbiology course combines practical hands-on
    laboratory and bioinformatics work with faculty lectures by, and
    discussions with, leaders in this crucial, exciting, and expanding area.
    The aim is to equip clinical scientists, specialist registrars, and
    consultants in infection disciplines with sufficient understanding of
    these areas to meet these challenges.

    The course will concentrate on the application of cutting-edge molecular
    and genomic techniques that can be implemented now, and explore new
    approaches that will enter practice in the near future. The programme
    will include sample collection and preparation, characterization of
    specimens with a variety of molecular techniques, and data interpretation
    using a variety of practical bioinformatic approaches.

    The practical part of the course will provide laboratory and computer
    sessions that will examine the application of molecular (and specifically
    genomic) techniques to three example clinical problems in:

    • Tuberculosis
    • Enteric infections
    • Encapsulated bacteria

    There will be demonstrations of the uses of different approaches in these
    clinical areas. Participants will use data generated on the course to
    make clinical and infection control decisions.

    Please note: Limited bursaries are available for
    clinical and academic applicants from anywhere in the world to attend
    this course, and are awarded on merit. In addition, CPD
    accreditation
    will be sought from the Royal College of
    Pathologists.

    Feedback from the 2016 course:

    • “This was the best course I have been on, bar none. It was a full schedule but very well paced and with plenty of time and opportunity to get into discussions with instructors/participants”
    • “Keep the course, it fills an important gap!”
    • “Overall, I thought the course was excellent and gave a real insight into the complexities and advantages of using genomic data and new sequencing approaches in my work. Thanks for the organisation and huge time commitment of the tutors. Also – what a fantastic group of participants! A real pleasure to meet everyone.”
    • “I would like to sincerely thank all the organisers of this course for a truly wonderful week.”
    • “One of the best courses I have attended – many thanks to all involved!”
  • Programme

    The programme will include lecture and practical
    laboratory/computer-based sessions covering a range of cutting-edge
    diagnostic techniques, including:

    • Design and implementation of real time PCR tests for pathogen detection
    • Molecular approaches to detect multiple pathogens
    • PCR-based typing
    • Whole genome sequencing
    • Mycobacterial typing and molecular bacterial load assays
    • Sequence-based isolate characterisation
    • Bioinformatics and data interpretation
    • Outbreak investigation

    Areas/issues that will be addressed in practical classes, demonstrations
    or lectures will include:

    • Specimen collection and contamination problems
    • Biological background to WGS approaches
    • Whole genome sequencing platforms and technologies
    • Technique discrimination – demonstrate how to choose the appropriate technique
    • Case studies demonstrating the relative merits of ‘genetics’ and ‘culture’
    • Developing a molecular diagnostic service

    Learning outcomes:
    Having completed the course participants will be able to:

    • explain the theoretical bases of pathogen genomics, including the application of population genomics to epidemiology and clinical microbiology
    • identify the currently available technologies for whole genome analysis and likely future developments
    • describe the clinical applications of genomics in developing diagnostics and evaluate their use in clinical settings
    • report on the latest research and development using state-of-the-art examples.

    In addition, participants will be able to:

    • perform a wide range of molecular analyses (including whole genome sequencing on diverse platforms) and molecular diagnostic techniques utlilising genomics
    • demonstrate data analysis using a wide variety of software, including variant mapping and gene-by-gene analysis
    • explain how the techniques, software, and theoretical approaches covered can be applied in real-world situations
  • Instructors / Speakers

    Course instructors
    Martin
    Maiden
    University of Oxford, UK
    Cath Arnold
    Public Health England, UK
    Stephen
    Gillespie
    University of St Andrews, UK
    Claire Jenkins Public Health England, UK

    Guest speakers will include:
    Xavier
    Didelot
    Imperial College London, UK
    Jennifer
    Gardy
    BC Centre for Disease Control, Canada
    Julian
    Parkhill
    Wellcome Trust Sanger Institute, UK
    Estée
    Torok
    University of Cambridge, UK

  • How to Apply

    Prerequisites
    Applicants should be clinical scientists, specialist registrars or
    consultants in medical microbiology.

    Cost
    The
    course is subsidised by the Wellcome Genome Campus
    Advanced Courses and Scientific Conferences Programme. This is a
    residential
    course and there is a fee of £775 towards
    board and lodging for non-commercial applicants. Please contact us for
    the commercial fee.

    Additional limited bursaries are available (up to 50%
    of the course fee)
    and are awarded on merit. Please see the “Bursaries”
    tab for details.

    Applications
    Applications for this course can be completed online. Places are limited
    and will be awarded on merit. If you have any problems with the online
    application process, please contact us.

    Please note: Applications
    must be supported by a
    recommendation from a scientific or clinical sponsor (e.g. supervisor or
    head of department). A request for a supporting
    statement will be sent
    to your nominated sponsor automatically during
    the application process.
    Applicants must ensure that their sponsor
    provides this supporting
    statement by the application deadline. Applications without a supporting
    statement cannot be considered.

    Deadlines
    Deadline for Applications: Closed

    Travel visas
    Please contact the
    event organiser if you require a letter to support a travel visa
    application. Note that letters will be provided to confirmed attendees.

    Non-European Economic Area or Swiss nationals may be required to have a
    visa to enter the UK.
    Early application is strongly advised, as this process can take 6-8 weeks
    or longer.

    Please visit the following websites for further information:
    UK Border Agency website and information for general visitors and business
    visitors.

  • Cost / Bursaries

    Cost
    The
    course is subsidised by the Wellcome Genome Campus Advanced Courses
    and
    Scientific Conferences Programme. This is a residential
    course and
    there is a fee of £775 towards board and lodging for
    non-commercial applicants. Please contact us for the commercial fee.

    Bursaries
    Advanced Courses are subsidised for non-commercial
    applicants from anywhere in the world. Additional, limited bursaries are
    available (up to 50% of the course fee) and are awarded on merit. If you
    would like to apply for a
    bursary, please complete the bursary section
    of the online application
    form.

    Please note that both the applicant
    and sponsor are required to provide
    a justification for the
    bursary as part of the application.

    Bursary terms and conditions

    UK Courses (held at the Wellcome Genome Campus, Hinxton,
    Cambridge)
    A
    limited number of bursaries are available for each course. These are
    awarded by the selection committee according to merit. The bursary
    covers a maximum of 50% of the course fee, though in exceptional
    circumstances an application for the total course fee may be considered.
    Where there are many bursary applications, the selection committee may
    issue smaller amounts. We cannot assist with travel costs to attend UK
    courses.

    Overseas Courses (held outside of the UK)
    A
    limited number of bursaries are available for each course. These are
    awarded on merit to cover travel, accommodation and sustenance. The
    maximum award for travel (economy class) will be £750.

    Bursaries can be applied for as part of the course application form.
    Applicants
    will be notified of a bursary award along with their place on
    the
    course, usually within one month of the application deadline. The
    decision of the selection committee is
    final.