This course type is lecture

Molecular Neurodegeneration

15 - 19 January 2018Wellcome Genome Campus, Hinxton, UK
Deadlines (at 23:59 UTC):
  • Bursary Deadline Closed
  • Application Deadline Closed

  • Summary

    This course provides an overview of the molecular basis of
    neurodegeneration and the development of therapeutic intervention to
    combat neurodegenerative disorders. The programme will focus on several
    disorders including Alzheimer’s disease, Parkinson’s disease, Fragile X,
    Spinocerebellar ataxia and amyotrophic lateral sclerosis. There are many
    parallels between different neurodegenerative disorders and the course
    will examine the common themes across neurodegenerative processes.
    Participants will gain an insight into the current understanding of both
    rare and common neurological disorders, the strengths and weaknesses of
    experimental approaches and evidence, recent developments in biomarkers
    and how this knowledge can be applied to develop therapies.

    The programme is aimed at individuals working in neurodegenerative
    research, neurogenetics or translational neuroscience, including
    clinician scientists, veterinary scientists, PhD students and
    post-doctoral researchers. We encourage applications from researchers
    based in the pharmaceutical and biotechnology industries. Applications
    from those who have completed a PhD in another area and have moved into
    neuroscience for their postdoctoral studies will also be considered.

    The course will benefit researchers who seek a comprehensive view of
    neurodegenerative disorders together with state of the art research
    techniques, and who wish to gain a new perspective on their own studies.
    The intensive programme provides the opportunity to interact with leading
    international neuroscientists. To optimize discussions and interactions,
    numbers are limited to 30 students.

    Learning outcomes
    After attending this course, participants will be able to:

    •    Describe in detail the process of
    •    Compare and contrast different neurological
    •    Critique a range of experimental techniques being
    used in neurogenetics
    •    Interpret and communicate the findings of a
    Genome-Wide Association Study
    •    Discuss the use of multiple biomarkers to diagnose
    neurodegenerative diseases
    •    Describe recent advances in therapeutic and
    translational areas to prevent and treat neurodegenerative diseases
    •    Apply concepts learned on the course to your own
    research project

    Feedback from previous participants

    “The whole course was an amazing experience and a great opportunity
    to get up to speed in such complex topics.”

    “The course really broadened my horizons as to the different powerful
    tools used for studying the mechanisms of disease.”

    “This is the best course I have been on. The interactive element to the
    course with fantastic speakers and a small group of participants is truly
    unique. The speakers and topics chosen perfectly complemented each other.
    By the end of the course key mechanisms and therapeutic strategies across
    the breadth of the neurodegenerative diseases were highlighted with
    important common themes emerging across diseases. I came away with lots
    of ideas to take to the lab.”

  • Programme

    The course will start at approximately 12.00 on Monday, 15 January and
    close at approximately 16.00 on Friday, 19 January 2018.

    The programme is lecture-based but highly interactive. Participants will
    have the opportunity to share their research with tutors, speakers and
    other students throughout the course, during the formal poster sessions
    and discussion sessions. Tutors are available throughout the course.

    Topics will include:

    • Pathological events in neurodegeneration
    • Autophagy, aging and neurodegeneration
    • Genetic variation in inherited and sporadic disease
    • RNA Genomics and bioinformatics
    • Use of in vivo models to study neurological pathogenesis
    • Modelling neurodegeneration using iPSCs
    • Development of therapeutic approaches

    Download a copy of the draft programme.

    This is a residential course. All students are requested to stay onsite
    for the full duration to benefit fully from discussions and interactions
    with the faculty and other students.

  • Instructors / Speakers

    Scientific programme committee
    Mark Cookson
    National Institutes of Health, USA
    Beverly Davidson
    The Children’s Hospital of Philadelphia and the
    University of Pennsylvania, USA
    Harry Orr
    University of Minnesota, USA 

    Nicholas Wood
    University College London, UK

    Confirmed tutors
    Karen Duff
    Columbia University, US
    Costantino Iadecola
    Weill Cornell Medical College,
    Rick Livesey
    University of Cambridge, UK
    Giovanna Mallucci
    Medical Research Council, UK
    Huw Morris
    University College London, UK
    David Nelson
    Baylor College of Medicine, USA
    Rita Sattler
    Barrow Neurological Institute, USA
    Sarah Tabrizi
    University College London, UK
    Yi Xing
    University of California, Los Angeles, USA

    Event organiser
    Lucy Criddle Wellcome Genome Campus, UK

  • How to Apply


    Registration with Single Accommodation  £750
    Commercial with Single Accommodation £1050

    The fees include accommodation, meals and lectures for the duration of
    the course. The fee will be requested once acceptance is confirmed.

    This is a residential course. All participants will stay at The Wellcome
    Genome Campus Conference Centre, Hinxton, Cambridge, for the nights of
    15, 16, 17, and 18 January 2018. For twin accommodation,  roommates
    will be allocated on a gender basis.

    If you wish to book onsite accommodation either side of the summer
    school/course dates, please contact the Conference

    Application deadline: Closed

    Places on this course are limited to 20 students and will be awarded on
    merit. Applicants should be PhD students currently engaged in relevant
    research and will be required to complete an online application form.

    The selection process will take place in November 2017.

    The following will need to be provided:

    • Qualifications and justification for attendance
    • A list of relevant publications
    • An outline of current research
    • Supervisor’s details: your supervisor will then receive an e-mail requesting a supporting statement to complete your application.

    Please note: Applications cannot be considered without a
    supervisor’s supporting statement.

    Travel visas
    Please contact the event organiser if you require a letter to support a
    travel visa application. Note that letters will be provided to confirmed

    Non-European Economic Area or Swiss nationals may be required to have a
    visa to enter the UK.
    Early application is strongly advised, as this process can take 6-8 weeks
    or longer.

    Please visit the following websites for further information:
    UK Border Agency website and information for general visitors and business

  • Bursaries

    A limited number of registration bursaries are
    available for PhD students to attend this course (up to 50% of the

    The following documents will need to be provided:

    • CV
    • Covering letter
    • Letter from supervisor

    To apply, please contact the event organiser.

    Bursary deadline: Closed

  • Sponsors

    If you are interested in supporting this event, please contact the event organiser.