Mouse Models of Disease: Improving Reproducibility of Pathology Endpoints in Challenge Models

09 - 11 February 2016Wellcome Genome Campus, Hinxton, UK
Deadlines (at 23:59 UTC):
  • Abstract Deadline Closed
  • Registration Deadline Closed

  • Summary

    The lack of reproducibility in biomedical science, particularly mouse
    model analyses, is hindering advances in our understanding of human
    disease and the development of novel therapies. This 3-day meeting will
    address this problem by sharing best practices in histopathology to
    ensure the generation of accurate data from mouse models.

    The meeting aims to bring together veterinary and human pathologists,
    scientists and technical specialists working with mouse models in
    academic and industrial research. The programme will start with a review
    of approaches to practical mouse pathology. This session will be
    accessible to students and experienced scientists who are new to mouse
    models and will enable participants to gain expertise in creating and
    interpreting reproducible mouse pathology data.

    A major focus of this year’s meeting will be the techniques used to
    investigate the pathology in the respiratory and gastrointestinal tracts
    in challenged and non-challenged phenotyping studies. Throughout the
    programme an emphasis will be placed on understanding the influence of
    environmental effects and experimental challenges on pathology endpoints
    and their potential effects on the reproducibility of data.

    This meeting has been CPD approved by the Royal College
    of Pathologists (17 credits).

  • Programme

    The meeting will start at approximately 09:45 on Tuesday, 9 February and close at approximately 16.45 on Thursday, 11 February 2016.

    Topics will include:

    • Mouse pathology: back to basics
    • Infectious diseases
    • Environmental factors
    • Infection models
    • Nutrition and diet
    • Microbiota
    • Lung function
    • Respiratory disease models
    • Imaging and validation
    • Reproducibility of lung cancer models
  • Organisers / Speakers

    Scientific programme committee
    Mark Arends
    University of Edinburgh, UK
    Cory Brayton
    Johns Hopkins School of Medicine, USA*

    Fiette Institut Pasteur,
    Aude Roulois
    GlaxoSmithKline, UK
    Cheryl Scudamore
    MRC Harwell, UK
    Mohamed Slaoui
    Sanofi R&D, France*
    Jacqui White
    Wellcome Trust Sanger Institute, UK
    Jonathan Williams
    Royal Veterinary College, UK

    Confirmed speakers
    Nicolau Beckmann Novartis Institutes for BioMedical
    Research, Switzerland
    Anton Berns
    The Netherlands Cancer Institute, The Netherlands

    Noel Downes Sequani, UK
    Craig Franklin
    University of Missouri, USA
    John Grainger
    University of Manchester, UK
    Patrick Hardy
    Sanofi Pasteur, France
    Deon Hildebrand GlaxoSmithKline, UK
    Dominique Kagele The Jackson Laboratory, USA
    Kevin Maloy University of Oxford, UK
    Wayne Mitzner
    Johns Hopkins University, USA
    Jonathan Stauber
    IMABIOTECH, France
    Graham Tobin Harlan Laboratories, UK

    Conference organiser
    Lucy Criddle Wellcome Genome Campus, UK

    *Funding generously provided by the Charles Louis Davis Foundation.

  • Registration / Accommodation

    Registration Fees:

    Student No accommodation £180.00
    Student On site twin accommodation £230.00
    Student On site single accommodation £260.00
    Academic No accommodation £280.00
    Academic On site twin accommodation £330.00
    Academic On site single accommodation £360.00
    Commercial No accommodation £380.00
    Commercial On site twin accommodation £430.00
    Commercial On site single accommodation £460.00
    Student Day delegate rate £70.00
    Academic Day delegate rate £100.00
    Commercial Day delegate rate £140.00

    The registration fee includes entrance to the lectures and poster
    sessions, an abstract book, meals (lunch and dinner) and refreshments
    during the conference. Breakfast will be provided for delegates who have
    booked accommodation.

    Registration deadline: Closed

    Accommodation is provided for the nights of 9 and 10 February 2016.
    Please note there is limited on-site accommodation and this will be
    allocated on a first-come first-served basis. Therefore, early
    registration is recommended.
    If you wish to book onsite accommodation either side of the conference
    dates, please contact the Conference Centre directly.

    Travel visas
    Contact the conference organiser if you require a letter to support a
    travel visa application. Note that letters will be provided to confirmed

    Non-European Economic Area or Swiss nationals may be required to have a
    visa to enter the UK. 
    Early application is strongly advised, as this process can take 6-8 weeks
    or longer.

    Please visit the following websites for further information:
    UK Border Agency website:

    Information for general visitors and business visitors:

  • Abstracts

    We welcome abstracts from all areas relevant to the main themes of the
    meeting, for oral and poster presentations. Several oral presentations
    will be chosen from the abstracts submitted.

    Please register prior to submitting your abstract. Please note: abstracts will only be considered from registered delegates.

    The scientific programme committee will assess your abstract after the
    deadline has passed and you will be notified whether you have been
    selected for an oral or poster presentation.

    Poster boards onsite will accommodate 118 cm high by 84 cm wide (A0-
    portrait) of printed material. Accepted abstracts will appear in the
    conference programme book and poster boards will be allocated at the

    Abstract deadline: Closed

    Abstract guidelines

    • Format & Font: Prepare your abstract in Microsoft Word in 11-point Ariel Font.
    • Title: The title should be concise and be in bold, sentence case.
    • Author names: The presenting author’s name must be the first name to appear on the list of authors. Underline the name of the presenting author. For each author give the forename followed by the surname.
    • Affiliations: Please list the authors and affiliations directly under the title, separated by one empty line, and followed on additional lines as necessary. Indicate each author’s affiliation with a superscript numeral following the surname.
    • Abstract length: should not exceed one 1.5-spaced page. The total word limit is 400 words (to include title, authors, affiliations and abstract narrative).
    • Abstract narrative: must be clear and concise. Clearly describe the problem you are addressing, the results to date and any conclusions you can draw from them, so that your abstract can be evaluated by the programme committee. Avoid saying in effect ‘a solution to XYZ problem will be presented’. Please ensure that your abstract is checked for correctness of spelling and grammar in advance of submission.
    • Subheadings: Please avoid the use of subheadings in the abstract narrative.
    • References: A separate list of references at the end of the abstract is not necessary.
    • File name: should be the same as the surname of the presenting author.
    • Download a sample abstract document (Microsoft Word), which can be used for formatting purposes.
  • Bursaries
  • Sponsors

    We thank the following organisations for their support.