NewThis course type is laboratory

RNA Transcriptomics

20 - 29 June 2018Wellcome Genome Campus, Hinxton, UK
Deadlines (at 23:59 UTC):
  • Deadline for Applications Closed
  • Application Deadline Closed

  • Summary

    Rapid advances in genome analysis technology have opened up new and
    exciting possibilities for studying the transcriptome and its function.

    In particular, third generation, single molecule sequencing technologies
    and single cell technologies, combined with perturbation tools, allow the
    analysis of complete RNA species – both short and long – at high
    resolution. In parallel, these tools have opened new ways in
    understanding gene functions at the tissue, network and pathway level, as
    well as detailed characterization of their function.

    This exciting new course will provide hands-on training in advanced
    laboratory and computational methodologies for the analysis of
    transcriptomes, including long non-coding RNAs and microRNAs, along with
    their post-transcriptional and epi-transcriptomic modification.

    The programme will focus on new technologies for direct RNA sequencing,
    and complete single molecule cDNA sequencing, single cell RNA sequencing
    and the characterisation and analysis of non-coding RNAs (such as lncRNAs
    and microRNAs). Analysis of the epi-transcriptome, including RNA
    methylation and modification, will also be covered.

    The practical programme will be complemented by distinguished guest
    speakers, who will present the latest research in this fast-moving field,
    along with opportunities for informal discussions.

  • Programme

    The course will include laboratory and computational practical sessions, along with lectures and discussions, covering the following topics:

    • Overview of single molecule long read sequencing technologies
    • Full length total RNA sequencing
    • Full length cDNA sequencing
    • Small RNA sequencing
    • Single cell transcriptome data generation and analysis
    • Identification of post-transcriptional modifications in RNA (epi-transcriptomics)
    • Functional assays for lncRNA biology
    • Integration of microRNA and mRNA data; functional analysis of microRNAs
    • Expression network and pathway integration and analysis

    Learning Outcomes
    After attending this course, participants should be able to:

    • Evaluate advanced RNA transcriptomic analysis methodologies and their applications
    • Appreciate different approaches currently in use to address specific research questions in the field
    • Assess the strengths, weaknesses and limitations of different methodologies and approaches
    • Integrate and apply the knowledge and training from the course to their own research interests
  • Instructors / Speakers

    Course Instructors
    Jiannis Ragoussis
    McGill University, Canada
    Anton Enright University of Cambridge, UK

    Francesca Buffa University of Oxford, UK
    Alena Shkumatava Curie Institute, France
    Martin Hemberg Wellcome Trust Sanger
    Institute, UK

    Guest Speakers
    Artemis Hatzigeorgiou University of Thessaly, Greece
    Michaela Frye Wellcome Trust-MRC Stem Cell Institute, UK
    Claus Nerlov University of Oxford, UK
    Donal O’Carroll University of Edinburgh, UK

  • How to Apply

    Prerequisites
    Applicants should be researchers or clinicians interested in applying
    advanced laboratory and computational methodologies for the analysis of
    transcriptomes, including long non-coding RNAs and microRNAs, as well as
    their post-transcriptional and epi-transcriptomic modification. It is
    suitable for PhD students working on a relevant project, postdoctoral
    trainees and fellows, as well as early career researchers.

    Applications
    Applications
    can be submitted online
    . Places are limited and will be awarded on
    merit. If you have any problems with the online application process,
    please contact
    us
    .

    Please note: Applications
    must be supported by a
    recommendation from a scientific or clinical
    sponsor (e.g. supervisor,
    line manager, or head of department). A
    request for a supporting
    statement will be sent to your nominated sponsor automatically during
    the application process. Applicants must ensure that their sponsor
    provides this supporting statement by the application deadline.
    Applications without a supporting statement cannot be
    considered.

    Deadlines
    Deadline for Applications: Closed

    Travel visas
    Please contact the
    event organiser if you require a letter to support a travel visa
    application to the UK. Note that letters will only be provided to confirmed attendees.

    Non-European Economic Area or Swiss nationals may be required to have a
    visa to enter the UK.
    Early application is strongly advised, as this process can take 6-8 weeks
    or longer.

    Please visit the following websites for further information:
    UK Border Agency website and information for general visitors and business
    visitors.

  • Cost / Bursaries

    Cost
    The course is subsidised by the Wellcome Genome Campus Advanced Courses
    and Scientific Conferences Programme. This is a residential course and
    the fee is £1110, including all accommodation and meals.
    This subsidised fee is available to all non-commercial applicants. Please
    contact us
    for the commercial fee.

    Bursaries
    Advanced Courses are subsidised for non-commercial applicants from
    anywhere in the world. Additional, limited bursaries are
    available (up
    to a 50% reduction of the course fee) and are awarded on merit. If you
    would like to apply for a
    bursary, please complete the bursary section
    of the online application
    form.

    Please note that both the applicant
    and sponsor are required to provide
    a justification for the
    bursary as part of the application.

    Additional funding opportunities
    Visit
    our Funding webpage
    for additional funding opportunities currently
    available.


    Bursary terms and conditions

    UK Courses (held at the Wellcome Genome Campus, Hinxton,
    Cambridge)
    A
    limited number of bursaries are available for each course. These are
    awarded by the selection committee according to merit. The bursary
    covers a maximum of 50% of the course fee, though in exceptional
    circumstances an application for the total course fee may be considered.
    Where there are many bursary applications, the selection committee may
    issue smaller amounts. We cannot assist with travel costs to attend UK
    courses.

    Bursaries can be applied for as part of the course application form.
    Applicants
    will be notified of a bursary award along with their place on
    the
    course, usually within one month of the application deadline. The
    decision of the selection committee is
    final.