Vesicle Trafficking & Pathways to Neurodegeneration (Virtual Conference)

17 - 19 May 2021
Deadlines (at 23:59 UTC):
  • Abstract deadline 23 March 2021
  • Registration deadline 10 May 2021

Registration opens soon.
email for updates.

  • Summary

    Alterations in vesicle trafficking are emerging as key elements in the underlying pathogenesis of dementia and diverse neurodegenerative diseases, such as Alzheimer’s, Parkinson’s, amyotrophic lateral sclerosis (ALS) and the spastic paraplegias.

    This new conference will build on links across these disorders to provide genetic and functional insights into the underlying etiology of neuronal cell death. Discussion will centre on neurodegeneration-related human genetics and endocytic trafficking regulation, including synaptic vesicle biology; lysosomal and endosomal dysfunction; mitochondrial biology; regulation of autophagy; and axonal transport disease. The challenges of translating mechanistic advances into therapeutic advances will be embedded into each session. We will also explore how novel technologies and large-scale data approaches can accelerate research in this area.

    This new forum aims to advance understanding of neurodegenerative disease biology and aid development of interventions that benefit patients.

    The conference will bring together clinicians specialising in neurology along with researchers from academia and industry involved in neurodegeneration across the spectrum of human genetics, fundamental cell biology and drug development.  We welcome abstracts on all major themes of this meeting to oral or poster presentations.

    Image by Camillo Golgi, with thanks to University History Museum, University of Pavia

  • Programme

    The conference will run from Monday 17 May until Wednesday 19 May 2021.
    Sessions will start at 13:00 and finish at approximately 18:00 each day.
    All times are given in British Summer Time (BST). See the time where you are here.

    Topics will include:

    • Axonal vesicle transport disruption
    • Neurodegeneration-associated autophagy
    • Lysosomal & endosomal dysfunction in neurodegenerative disease
    • Mitochondrial biology of neurodegeneration
    • Synaptic dysfunction in neuropathogenesis
    • Genetic links to vesicle trafficking dysfunction

    Discussions on drug discovery and therapeutic interventions will be embedded in each session.

  • Organisers/ Speakers

    Scientific programme committee

    Craig Blackstone

    Craig Blackstone
    Massachusetts General Hospital - Harvard, USA

    Fiona Elwood

    Fiona Elwood
    Novartis, USA

    Patrick Lewis

    Patrick Lewis
    Royal Veterinary College, UK

    Helene Plun-Favreau

    Helene Plun-Favreau
    University College London, UK

    Keynote speakers

    Pietro De Camilli

    Pietro De Camilli
    Yale School of Medicine, USA

    Confirmed speakers

    Alison Goate (Mount Sinai Medical School, USA)
    Erika Holtzbaur (University of Pennsylvania, USA)
    Henry Houlden (University College London, UK)
    Michael Lazarou (Monash University, Australia)
    Heidi McBride (McGill University, Canada)
    Ira Milosevic (University of Oxford, UK)
    Beat Nyfeler (Novartis, Switzerland)
    Helene Plun-Favreau (University College London, UK)
    Margaret Robinson (University of Cambridge, UK)
    Pablo Sardi (Sanofi, USA)
    Giampietro Schiavo (University College London, UK)
    Patrik Verstreken (VIB-KU Leuven, Belgium)

    Conference organisers

    Amanda Fletcher – Conference & Events Organiser
    Jane Murphy – Scientific Programme Officer

  • Registration
    Student £50
    Delegates from LMICs* £50
    Academic £100
    Commercial £150

    The virtual registration package includes: Access to all live-streamed sessions (including poster sessions and online networking channels), as well as access to all sessions ‘on-demand’ for four weeks after the event.

    *To increase the international diversity of attendees at our meetings, we have reduced fees for delegates from Lower and Middle Income Countries (see list of countries here). If you are in need of financial support and would like to apply for a bursary, please contact the conference organiser. When applying for a bursary you will be asked to provide a letter stating financial need and a CV.

    Log in details for the virtual conference portal will be provided on Thursday before the event.

  • Abstracts

    We welcome abstracts from all areas relevant to the main themes of the meeting, for both oral and poster presentations. Several oral presentations will be chosen from the abstracts submitted.

    Abstracts will only be considered from registered delegates. Please use our online abstract submission system and follow the instructions given to ensure your abstract is submitted correctly. All abstracts must be submitted by the deadline. If you are intending to submit more than one abstract, please contact the conference organiser prior to registration.

    The scientific programme committee will assess your abstract after the deadline has passed and you will be notified whether you have been selected for an oral or poster presentation.

    All those accepted for a poster presentation will be given the opportunity to upload a short video describing their work.

    Abstract deadline: 23 March 2021

    How to upload an abstract once you have already completed registration:

    1. Log back into your registration account using either Firefox or Internet Explorer as your browser, via link above the ‘Share’ button on the right hand column of this page
    2. Click on ‘Account’ (top right).
    3. Then click on ‘View account history’. This will show a table of your event registrations.
    4. In the right-hand column you will see the option to ‘Upload file’ – click on this and select to upload an abstract.
  • Sponsors